COMMUNICATIONS REACTION OF ANIMAL EYES TO SANGUINARINE AND ARGEMONE OIL

Argemone oil, sanguinarine, and epidemic-dropsy glaucoma.

Argemone mexicana Linn. (Linnaeus, 1753; Tournefort, 1694), is a herb of the Papaveraceae (poppy family) indigenous to the West Indies (Fig. 1). The study of this herb and its active principles is important, first to circumvent the serious epidemics of dropsy and glaucoma resulting from the unintentional ingestion of its seed oil in tropical countries; secondly to find a method of producing in ...

Argemone Oil

Detection of argemone oil in mustard oil.

Effect of Argemone Oil on Monkeys

came acute, urine was suppressed, pupils dilated and the animal died at 12 a.m. on 16th February, 1951. Postmortem appearance.?Weight 11.5 lbs. Peritoneal cavity contained 10 cc. of strawcoloured fluid. Mucus membrane of stomach congested. Hemorrhagic points in the duodenum. Wall of lower jejunum and ileum thinned out, leaving only the peritoneal layer, lower down necrotic areas and acute conge...

Sanguinarine and Dihydrosanguinarine Accumulation in Argemone mexicana (L) Cell Suspension Cultures Exposed to Yeast Extract 19 Sanguinarine and Dihydrosanguinarine Accumulation in Argemone mexicana (L) Cell Suspension Cultures Exposed to Yeast Extract

Alkaloid contents in Argemone mexicana cell line AMMiF were analyzed during a 36-day culture cycle. The benzophenanthridine sanguinarine (SA) represented the main alkaloid. Dihydrosanguinarine (DHSA), a SA biosynthetic precursor and a less toxic benzophenanthridine, was also identified, based on chromatographic properties and further confirmed by gas chromatography coupled to mass spectrometry....